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Principal Investigator and Lab Manager

Dave Langenau (PI)   David received his B.S. and M.S. from the University of Notre Dame and his Ph.D. in Biology and Biomedical Sciences from Harvard Medical School in 2004. He next completed his fellowship training at Children’s Hospital Boston in 2008. Along with Dr. A. Thomas Look, he is credited with developing the first transgenic zebrafish model of cancer. In his own group, he has made seminal discoveries underlying the pathogenesis of pediatric acute lymphoblastic leukemia and rhabdomyosarcoma. He enjoys swimming, fishing, golfing, and bicycling with his two boys and wife.

Dave Langenau (PI)

David received his B.S. and M.S. from the University of Notre Dame and his Ph.D. in Biology and Biomedical Sciences from Harvard Medical School in 2004. He next completed his fellowship training at Children’s Hospital Boston in 2008. Along with Dr. A. Thomas Look, he is credited with developing the first transgenic zebrafish model of cancer. In his own group, he has made seminal discoveries underlying the pathogenesis of pediatric acute lymphoblastic leukemia and rhabdomyosarcoma. He enjoys swimming, fishing, golfing, and bicycling with his two boys and wife.

Karin McCarthy (Lab Manager)   *bio under construction; check back soon!

Karin McCarthy (Lab Manager)

*bio under construction; check back soon!

 

Post-Doctoral Fellows

Alessandra Welker   Alessandra graduated from Colby College in 2011 with a BA in Psychology and Biology, and a minor in Italian studies and Film studies. After college, she attended THE Ohio State University for Graduate School, where she graduated with a PhD in Neuroscience in 2016. Her thesis work generated and characterized a novel model of the aggressive brain cancer Glioblastoma in zebrafish. While in Columbus, she attended lots of football games and sporting events. Go Buckeyes! In the Langenau Lab, she is interested in studying developmental pathways that are switched back on in rhabdomyosarcoma. In her free time, Alessandra loves to travel with her family to their houses in Martha’s Vineyard and Umbria, Italy. She also likes to visit friends, plan parties, watch sports, attend concerts and shows, cook and try new restaurants.

Alessandra Welker

Alessandra graduated from Colby College in 2011 with a BA in Psychology and Biology, and a minor in Italian studies and Film studies. After college, she attended THE Ohio State University for Graduate School, where she graduated with a PhD in Neuroscience in 2016. Her thesis work generated and characterized a novel model of the aggressive brain cancer Glioblastoma in zebrafish. While in Columbus, she attended lots of football games and sporting events. Go Buckeyes! In the Langenau Lab, she is interested in studying developmental pathways that are switched back on in rhabdomyosarcoma. In her free time, Alessandra loves to travel with her family to their houses in Martha’s Vineyard and Umbria, Italy. She also likes to visit friends, plan parties, watch sports, attend concerts and shows, cook and try new restaurants.

Chuan Yan   Yan was born in China but moved to Singapore with his parents at the age of 7. He graduated with a PhD from the National University of Singapore in 2016, focusing on using zebrafish to model human liver cancer. In the Langenau lab, Yan works on developing immune compromised zebrafish models that are capable of engrafting various human and mice cells, and establishing various protocols that help in the engraftment of these foreign tissues. Outside of lab, Yan spends most of his time online shopping as a coping mechanism for lab-induced stress.

Chuan Yan

Yan was born in China but moved to Singapore with his parents at the age of 7. He graduated with a PhD from the National University of Singapore in 2016, focusing on using zebrafish to model human liver cancer. In the Langenau lab, Yan works on developing immune compromised zebrafish models that are capable of engrafting various human and mice cells, and establishing various protocols that help in the engraftment of these foreign tissues. Outside of lab, Yan spends most of his time online shopping as a coping mechanism for lab-induced stress.

Alexandra Veloso   Alexandra is a post-doctoral fellow from Portugal, with a Masters in Biochemistry and Cellular and Molecular Biology with Distinction and a PhD from the University of Liege in Belgium, studying the functions of three members of the SoHo involved in zebrafish angiogenesis. In the Langenau Lab, Alexandra works to generate novel B cell acute lymphoblastic leukemia (B-ALL) models in zebrafish and characterize their clonal evolution and cell of origin. Outside of lab, Alexandra enjoys the Marvel Cinematic Universe, running, and is hopelessly addicted to coffee.

Alexandra Veloso

Alexandra is a post-doctoral fellow from Portugal, with a Masters in Biochemistry and Cellular and Molecular Biology with Distinction and a PhD from the University of Liege in Belgium, studying the functions of three members of the SoHo involved in zebrafish angiogenesis. In the Langenau Lab, Alexandra works to generate novel B cell acute lymphoblastic leukemia (B-ALL) models in zebrafish and characterize their clonal evolution and cell of origin. Outside of lab, Alexandra enjoys the Marvel Cinematic Universe, running, and is hopelessly addicted to coffee.

 
Yun (Claudia) Wei   Claudia is a research fellow especially interested in rhabdomyosarcoma, utilizing the patient-derived xenograft mouse model along with the developmental STAR zebrafish. She got her Bachelor's degree in Wuhan University back in China, and then moved to another warm city, Atlanta, to pursue a PhD in Cancer Biology at Emory University. For her dissertation, she worked with her mentor Anna Marie Kenney to investigate the aberrant cell signaling in pediatric brain tumors medulloblastoma. She likes to play badminton, bike, or jog during her free time. She is also a big fan of board games; no gambling though!

Yun (Claudia) Wei

Claudia is a research fellow especially interested in rhabdomyosarcoma, utilizing the patient-derived xenograft mouse model along with the developmental STAR zebrafish. She got her Bachelor's degree in Wuhan University back in China, and then moved to another warm city, Atlanta, to pursue a PhD in Cancer Biology at Emory University. For her dissertation, she worked with her mentor Anna Marie Kenney to investigate the aberrant cell signaling in pediatric brain tumors medulloblastoma. She likes to play badminton, bike, or jog during her free time. She is also a big fan of board games; no gambling though!

Tiffany Eng   *bio under construction; check back soon!

Tiffany Eng

*bio under construction; check back soon!

Qiqi Yang   *bio under construction; check back soon!

Qiqi Yang

*bio under construction; check back soon!

Qian (Alvin) Qin   Alvin is from Shanghai, China, and he graduated from Tongji University in 2017 with a Ph.D. in Bioinformatics, especially for epigenomics study. He is now a postdoc research fellow co-mentored by Professor David Langenau and Professor Luca Pinello. Before he joined the lab, he was an assistant researcher at Children’s Hospital of Fudan University, where he integrated multi-modal MRI datasets for neonatal encephalopathy diagnosis with deep learning. His current interest lies in single-cell data integration across species and samples to construct the gene regulatory network and detect functional cis-elements underlying the mechanisms of oncogenesis and development, and potentially single cell microscopy images analysis for quantifying cell phenotype. Outside of lab, Alvin enjoys reading, swimming, and working out with his colleagues.

Qian (Alvin) Qin

Alvin is from Shanghai, China, and he graduated from Tongji University in 2017 with a Ph.D. in Bioinformatics, especially for epigenomics study. He is now a postdoc research fellow co-mentored by Professor David Langenau and Professor Luca Pinello. Before he joined the lab, he was an assistant researcher at Children’s Hospital of Fudan University, where he integrated multi-modal MRI datasets for neonatal encephalopathy diagnosis with deep learning. His current interest lies in single-cell data integration across species and samples to construct the gene regulatory network and detect functional cis-elements underlying the mechanisms of oncogenesis and development, and potentially single cell microscopy images analysis for quantifying cell phenotype. Outside of lab, Alvin enjoys reading, swimming, and working out with his colleagues.


Bioinformaticians

Sowmya Iyer   Sowmya was born in India, but has been in the US for almost 20 years now. She have a PhD in Bioinformatics from Boston University. As Computational Biologist here at MGH, Sowmya help multiple labs in Molecular Pathology make sense of the rich and varied -omics data they generate.  “I got two kids and no life, so I live vicariously through Groupon ads for beach destinations.”

Sowmya Iyer

Sowmya was born in India, but has been in the US for almost 20 years now. She have a PhD in Bioinformatics from Boston University. As Computational Biologist here at MGH, Sowmya help multiple labs in Molecular Pathology make sense of the rich and varied -omics data they generate.

“I got two kids and no life, so I live vicariously through Groupon ads for beach destinations.”

Sara Garcia   *bio under construction; check back soon!

Sara Garcia

*bio under construction; check back soon!

 

Research Technician

Daniel Do   Dan is a native of Lynn, MA, and he graduated from Bowdoin College in 2018 with a B.A. in Chemistry, with honors, and a minor in Visual Arts. In the Langenau Lab, he assists Chuan and Qiqi with their research projects as well as the maintenance and care of the zebrafish. Outside of lab, Dan likes to move heavy objects up and down repetitively (ie. lifting weights), shoot projectiles through metal loops (ie. playing basketball), and be a hero in his nightlife (ie. crushing video games).

Daniel Do

Dan is a native of Lynn, MA, and he graduated from Bowdoin College in 2018 with a B.A. in Chemistry, with honors, and a minor in Visual Arts. In the Langenau Lab, he assists Chuan and Qiqi with their research projects as well as the maintenance and care of the zebrafish. Outside of lab, Dan likes to move heavy objects up and down repetitively (ie. lifting weights), shoot projectiles through metal loops (ie. playing basketball), and be a hero in his nightlife (ie. crushing video games).